EXECUTIVE SUMMARY
INTRODUCING
ROCKETVAX
a platform developing next-generation viral vaccines for emerging COVID-19 variants and other infectious diseases
Rocketvax is developing next-generation vaccines leveraging the live-attenuated virus technology in response to the extensive unmet medical need in treatment and prevention of infectious diseases.
Two of the Company’s lead candidates, sCPD9 and OTS, are targeting the vast underserved market of novel COVID-19 variants, which will allow to both manage current and emergent treatment-resistant variants and prevent the risk of yet another future pandemic, while significantly streamlining administration through needle-free nasal delivery.

20+
Novel variants
in 2024
#1
Excellent Safety Profile
3x
Higher efficacy
$79b
Addressable Market

THE CHANGING
GLOBAL THREAT
OF COVID-19
2024 FIGURES
44K
COVID Deaths in the US
17.8%
Peak seroprevalence rates
>80%
Of COVID cases caused by new variants
16.5
Peak hospitalization (per 100,000)

Although the impact of COVID-19 is no longer as visible as during the peak lockdown period, there is no doubt COVID-19 is here to stay, transitioning to a global endemic.
In 2024, COVID remains a public health threat and the virus continues to mutate causing periodic surges, with majority of new diagnoses caused by novel variants which cannot be effectively mitigated by currently available vaccines.
CURRENTLY AVAILABLE VACCINE OPTIONS
ALL FALL SHORT
DECLINING
EFFICACY
Efficacy wanes over time, with an estimated 2x drop in effective protection from infection and death after 22 weeks.
LONG-TERM
PROTECTION
Dominant vaccines demonstrate limited efficacy against novel variants, with long-term efficacy against Delta as low as 3%-9%.
DELIVERY
LIMITATIONS
Currently available vaccines are all injectable, which adds incision risks and creates several supply chain limitations.

Rocketvax Platform
The Rocketvax platform develops next-generation live-attenuated virus vaccines, including a novel nasal vaccine candidate for SARS-CoV-2.
The lead candidate has demonstrated excellent results in animal studies, showcasing tremendous promise to offer superior patient outcomes for both existing and emerging COVID-19 variants.
LONG-TERM
IMMUNITY
DIFFERENTIATED
TECHNOLOGY
EFFECTIVE
BOOSTER
HIGHLY
SCALABLE
NEEDLE-FREE
DELIVERY
BROAD
EFFICACY
ESTABLISHED
SUPPLY CHAIN
EXCELLENT
TOLERABILITY
STABLE
FORMULATION

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